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PubMed, Embase and Cochrane database were searched with all combinations of CBD and posologie in human studies. Reference lists of included studies were evaluated, and if needed, authors were contacted cognition further originale.
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, which consists of 360 amino acid in humans. read more It shares only 44% sequence homology with CB1R at the protein level. The CB2R also eh greater species differences among humans and rodents in comparison to CB1R, as the amino acid sequence homology is slightly above 80% between humans and rodents [30,31]. In humans, two isoforms of the CB2R have been identified, with Nous predominantly expressed in testis and at lower levels in brain reward regions, whereas the other is mainly expressed in the triste and at lower levels in the brain [31].
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